This supplement, with the strange name, plays a crucial role in good health. One in three Americans have a genetic mutation that prevents them from properly utilizing folic acid, also known as vitamin B9. Folic acid is important to our health, due in part to its role in a biochemical process called methylation. The important thing to know here is that methylation, which should occur billions of times a day in the body, is essential for our health.

Folic acid is the synthetic form, used to fortify foods, and it is available in supplement form. 5-MTHF, also called methyltetrahydrofolate, or more simply, methylfolate, is the metabolically active form of folic acid. It is found in certain whole, unfortified foods, like raw leafy greens. This form of folic acid has to be separated from its protein carriers, in the body, in order to be absorbed.

Once absorbed, folic acid has to undergo several biochemical conversations to become 5-MTHF. Half of all Americans have genetically insufficient enzymes to create 5-MTHF. Which is a long explanation for why taking a 5-MTHF supplement is so critical. Millions of people can experience improved health and a longer life taking 5-MTHF, and since most of us don’t know whether we have the mutant or impaired genes or not, it becomes important that we all take this supplement daily.


5-MTHF helps with DNA synthesis and repair. Having adequate levels of 5-MTHF reduces the risks for tumors and certain types of cancers, including childhood leukemia, breast, colon, cervical and lung cancers, helps to prevent depression, and eases arthritis symptoms.

This supplement reduces homocysteine levels. High levels of this amino acid damage arteries, which contributes to heart disease, and can also cause stroke, deep vein thrombosis, peripheral vascular disease, depression, miscarriage, birth defects, hearing loss, osteoporosis, cancer, arthritis, dementia, Alzheimer’s, Parkinson’s and diabetes complications.

According to Anthony William, in his books Medical Medium and Thyroid Healing, 5-MTHF helps strengthen the endocrine system and the central nervous system. It is extremely helpful for supporting reproductive health that has been compromised by the Epstein Barr virus. This supplement is an ally in healing from EBV caused issues such as infertility, endometriosis and PCOS.

I began taking this supplement to help heal and support my central nervous system, after 20+ years of inflamed sciatic nerves due to the shingles virus. After learning about how important 5-MTHF is to overall good health and longevity, I’ve continued to take it daily, long after my sciatic nerves healed.

I purchase and take the capsules, which are very inexpensive, while also eating foods that contain this form of folic acid. That list of foods includes raw leafy greens, beets, legumes, onions, tomatoes, cruciferous vegetables, shiitake mushrooms, citrus fruits, berries, seeds, rosemary and curcumin. It’s a simple, daily practice that is reaping huge health benefits in my life.


You can purchase 5-MTHF by clicking the link below.

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2 thoughts on “5-MTHF”

  1. Is it dangerous to take this supplement daily, for a long period of time? The warnings state that it cause other health issues if taken long term.

    1. I take it for 4-6 weeks then stop for about that long. I’ve been taking it though for four years. I’ll check into it further though so thanks for mentioning it.

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